PM2.5 induce lifespan reduction, insulin/IGF-1 signaling pathway disruption and lipid metabolism disorder in Caenorhabditis elegans

• Main Authors: Wenjing Zhang (Author), Zinan Li (Author), Guojun Li (Author), Ling Kong (Author), Haiming Jing (Author), Nan Zhang (Author), Junyu Ning (Author), Shan Gao (Author), Yong Zhang (Author), Xinyu Wang (Author), Jing Tao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionExposure to fine particulate matter (PM), especially PM2.5, can induce various adverse health effects in populations, including diseases and premature death, but the mechanism of its toxicity is largely unknown.MethodsWater-soluble components of PM2.5 (WS-PM2.5) were collected in the nor...