Hydrotalcite Intercalated siRNA: Computational Characterization of the Interlayer Environment

• Main Authors: Sean C. Smith (Author), Zhiping Xu (Author), Vinuthaa Murthy (Author), Hong Zhang (Author), Yunyi Wong (Author), Defang Ouyang (Author)
• Format: Book
• Published: MDPI AG, 2012-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Using molecular dynamics (MD) simulations, we explore the structural and dynamical properties of siRNA within the intercalated environment of a <em>Mg</em>:<em>Al</em> 2:1 Layered Double Hydroxide (LDH) nanoparticle. An <em>ab initio</em> force field (Condensed-ph...