Hydrotalcite Intercalated siRNA: Computational Characterization of the Interlayer Environment

• Autori principali: Sean C. Smith (Autore), Zhiping Xu (Autore), Vinuthaa Murthy (Autore), Hong Zhang (Autore), Yunyi Wong (Autore), Defang Ouyang (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2012-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Using molecular dynamics (MD) simulations, we explore the structural and dynamical properties of siRNA within the intercalated environment of a <em>Mg</em>:<em>Al</em> 2:1 Layered Double Hydroxide (LDH) nanoparticle. An <em>ab initio</em> force field (Condensed-ph...