Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma

• Main Authors: Jian-Hong Qi (Author), Dong-Chuan Xu (Author), Xiao-Long Wang (Author), Ding-Yuan Cai (Author), Yi Wang (Author), Wei Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Asthma is a common chronic respiratory disease, which causes inflammation and airway stenosis, leading to dyspnea, wheezing and chest tightness. Using transgelin-2 as a target, we virtually screened the lead compound glycyrrhizin from the self-built database of anti-asthma compounds by molecular doc...