Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors

AbstractA novel series of 1,2,3-triazole/1,2,4-oxadiazole hybrids (7a-o) was developed as dual inhibitors of EGFR/VEGFR-2. Compounds 7a-o were evaluated as antiproliferative agents with Erlotinib as the reference drug. Results demonstrated that most of the tested compounds showed significant antipro...

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Asıl Yazarlar: Mohamed A. Mahmoud (Yazar), Anber F. Mohammed (Yazar), Ola I. A. Salem (Yazar), Tahani Mazyad Almutairi (Yazar), Stefan Bräse (Yazar), Bahaa G. M. Youssif (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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