HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

• Główni autorzy: Marina R. Tavares (Autor), Klára Hrabánková (Autor), Rafał Konefał (Autor), Martin Kaňa (Autor), Blanka Říhová (Autor), Tomáš Etrych (Autor), Milada Šírová (Autor), Petr Chytil (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The study describes the synthesis, physicochemical properties, and biological evaluation of polymer therapeutics based on <i>N</i>-(2-hydroxypropyl)methacrylamide (HPMA) copolymers intended for a tumor-targeted immuno-oncotherapy. Water-soluble linear and cholesterol-containing HPMA prec...