A randomised, double-blind, controlled efficacy trial of the LiESP/QA-21 vaccine in naïve dogs exposed to two leishmania infantum transmission seasons.

• Main Authors: Gaetano Oliva (Author), Javier Nieto (Author), Valentina Foglia Manzillo (Author), Silvia Cappiello (Author), Eleonora Fiorentino (Author), Trentina Di Muccio (Author), Aldo Scalone (Author), Javier Moreno (Author), Carmen Chicharro (Author), Eugenia Carrillo (Author), Therese Butaud (Author), Laurie Guegand (Author), Virginie Martin (Author), Anne-Marie Cuisinier (Author), David McGahie (Author), Sylvie Gueguen (Author), Carmen Cañavate (Author), Luigi Gradoni (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Canine leishmaniasis is an important zoonosis caused by uncontrolled infection with Leishmania infantum, where an inappropriate immune response is not only responsible for permitting this intracellular parasite to multiply, but is also responsible for several of the pathological processes seen in th...