Ouabain-mediated downregulation of ALKBH5 and IGF2BP2 inhibits the malignant progression of DLBCL

• Main Authors: Yuxin Hong (Author), Hehua Ma (Author), Haoyi Yang (Author), Yuning Zhu (Author), Yuan Wei (Author), Zhenzhen Xu (Author), Yuwen Zhang (Author), Dandan Jin (Author), Zhiyou Chen (Author), Wei Song (Author), Juan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

m6A modification is a crucial epigenetic regulatory mechanism in diffuse large B-cell lymphoma (DLBCL). Low-dose cardiotonic drugs have been shown to induce apoptosis in DLBCL cells through epigenetic modulation. However, the involvement of the cardiotonic drug ouabain in the malignant progression o...