Structural Examination of 6-Methylsulphonylphenanthro- [9,10-C]-furan-1(3H)-one-A Rofecoxib Degradation Product
In the attempt to discover a new polymorph of rofecoxib (Vioxx®), an unexpected product resulted. The product was characterised by chemical composition, thermal behaviour and structure and found to be 6-methylsulphonylphenanthro-[9,10-C] furan-1(3H)-one, a photo-cyclization degradation product of ro...
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MDPI AG,
2010-02-01T00:00:00Z.
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