Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901

• Главные авторы: Zhiying Ai (Автор), Jingjing Shao (Автор), Xinglong Shi (Автор), Mengying Yu (Автор), Yongyan Wu (Автор), Juan Du (Автор), Yong Zhang (Автор), Zekun Guo (Автор)
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• Опубликовано: Hindawi Limited, 2016-01-01T00:00:00Z.
• Предметы: article
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Embryonic stem cells (ESCs) have the ability to grow indefinitely and retain their pluripotency in culture, and this self-renewal capacity is governed by several crucial molecular pathways controlled by specific regulatory genes and epigenetic modifications. It is reported that multiple epigenetic r...