Penicilliumin B Protects against Cisplatin-Induced Renal Tubular Cell Apoptosis through Activation of AMPK-Induced Autophagy and Mitochondrial Biogenesis

• Main Authors: Weiwei Shen (Author), Nan Jia (Author), Jinhua Miao (Author), Shuangqin Chen (Author), Shan Zhou (Author), Ping Meng (Author), Xuefeng Zhou (Author), Lan Tang (Author), Lili Zhou (Author)
• Format: Book
• Published: Karger Publishers, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Acute kidney injury (AKI) is at a high prevalence in hospitalized patients, especially in those receiving chemotherapy. Cisplatin is the most widely used chemotherapy drug; however, with its side effects that include nephrotoxicity, it also exhibits a risk of inducing AKI. Importantly,...