A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea

• Main Authors: Andromeda Van Roten (Author), Amal Zohir Abo-Zeid Barakat (Author), Annelies Wouters (Author), Thao Anh Tran (Author), Stijn Mouton (Author), Jean-Paul Noben (Author), Luca Gentile (Author), Karen Smeets (Author)
• Format: Book
• Published: The Company of Biologists, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Planarians have been long known for their regenerative ability, which hinges on pluripotency. Recently, however, the planarian model has been successfully established for routine toxicological screens aimed to assess overproliferation, mutagenicity and tumorigenesis. In this study, we focused on pla...