Design of Polymeric Nanocapsules for Intranasal Vaccination against Mycobacterium Tuberculosis: Influence of the Polymeric Shell and Antigen Positioning

• Main Authors: Lara Diego-González (Author), José Crecente-Campo (Author), Matthew John Paul (Author), Mahavir Singh (Author), Rajko Reljic (Author), María José Alonso (Author), África González-Fernández (Author), Rosana Simón-Vázquez (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tuberculosis (TB) is the leading cause of death from a single infectious microorganism and Bacillus Calmette Guerin (BCG), the only authorized vaccine, does not confer protection against pulmonary TB. Based on the hypothesis that mucosal protection could help to prevent the infection at the site of...