Polymeric Particle BAM15 Targeting Macrophages Attenuates the Severity of LPS-Induced Sepsis: A Proof of Concept for Specific Immune Cell-Targeted Therapy

• Главные авторы: Kanyarat Udompornpitak (Автор), Thansita Bhunyakarnjanarat (Автор), Wilasinee Saisorn (Автор), Chonnavee Manipuntee (Автор), Kittawat Plengplang (Автор), Samarch Sittichaitaweekul (Автор), Panisa Jenphatanapong (Автор), Suwasin Udomkarnjananun (Автор), Warerat Kaewduangduen (Автор), Kasirapat Ariya-anandech (Автор), Amanee Samaeng (Автор), Numpon Insin (Автор), Patcharee Ritprajak (Автор), Asada Leelahavanichkul (Автор)
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• Опубликовано: MDPI AG, 2023-11-01T00:00:00Z.
• Предметы: article
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Macrophage polarization requires different energy sources and metabolic processes. Therefore, cell energy interference to alter macrophage functions has been proposed as a treatment for severe inflammatory diseases, including sepsis. In this study, targeting cell energy using BAM15 (a mitochondrial...