Pharmacokinetics, safety, and simulated efficacy of an influenza treatment, baloxavir marboxil, in Chinese individuals

• Main Authors: Yanmei Liu (Author), Sylvie Retout (Author), Vincent Duval (Author), Jingying Jia (Author), Yang Zou (Author), Yijun Wang (Author), Valérie Cosson (Author), Sébastien Jolivet (Author), Stefan De Buck (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Baloxavir marboxil is an endonuclease inhibitor indicated for the treatment of influenza in patients ≥12 years. No data exist for Chinese patients in global studies. This randomized, open‐label, phase I study evaluated the pharmacokinetics (PK) and safety of baloxavir marboxil in healthy Ch...