Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice

• Main Authors: Qiuyan Guo (Author), Jiangpeng Wu (Author), Qixin Wang (Author), Yuwen Huang (Author), Lin Chen (Author), Jie Gong (Author), Maobo Du (Author), Guangqing Cheng (Author), Tianming Lu (Author), Minghong Zhao (Author), Yuan Zhao (Author), Chong Qiu (Author), Fei Xia (Author), Junzhe Zhang (Author), Jiayun Chen (Author), Feng Qiu (Author), Jigang Wang (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tripterygium glycosides tablet (TGT), the classical commercial drug of Tripterygium wilfordii Hook. F. has been effectively used in the treatment of rheumatoid arthritis, nephrotic syndrome, leprosy, Behcet's syndrome, leprosy reaction and autoimmune hepatitis. However, due to its narrow and li...