5-Bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one targets prostate cancer cells by down-regulating inflammation-related genes

• Main Authors: Zhao-Yang Wang (Author), Jun-Yong Wang (Author), Jun Zhang (Author), Kai Zhang (Author), Rui Fan (Author), Jun-Hao Niu (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study was performed to examine the effect of 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one (BHP) on the rate of cell proliferation and apoptosis induction in the PC3, human prostate carcinoma cell line. The cell viability was assayed by using sulphorhodamine B staining and apoptosis by...