Vitamin C Cytotoxicity and Its Effects in Redox Homeostasis and Energetic Metabolism in Papillary Thyroid Carcinoma Cell Lines

• Үндсэн зохиолчид: Laura Tronci (Зохиогч), Gabriele Serreli (Зохиогч), Cristina Piras (Зохиогч), Daniela Virginia Frau (Зохиогч), Tinuccia Dettori (Зохиогч), Monica Deiana (Зохиогч), Federica Murgia (Зохиогч), Maria Laura Santoru (Зохиогч), Martina Spada (Зохиогч), Vera Piera Leoni (Зохиогч), Julian Leether Griffin (Зохиогч), Roberta Vanni (Зохиогч), Luigi Atzori (Зохиогч), Paola Caria (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

High-dose of vitamin C (L-ascorbic acid, ascorbate) exhibits anti-tumoral effects, primarily mediated by pro-oxidant mechanisms. This cytotoxic effect is thought to affect the reciprocal crosstalk between redox balance and cell metabolism in different cancer types. Vitamin C also inhibits the growth...