Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

• Κύριοι συγγραφείς: Josephine M. Kanta (Συγγραφέας), Luisa Deisen (Συγγραφέας), Kornelia Johann (Συγγραφέας), Stephanie Holm (Συγγραφέας), Annemarie Lundsgaard (Συγγραφέας), Jens Lund (Συγγραφέας), Markus Jähnert (Συγγραφέας), Annette Schürmann (Συγγραφέας), Christoffer Clemmensen (Συγγραφέας), Bente Kiens (Συγγραφέας), Andreas M. Fritzen (Συγγραφέας), Maximilian Kleinert (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2023-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Objective: Medium chain fatty acids (MCFAs), which are fatty acids with chain lengths of 8-12 carbon atoms, have been shown to reduce food intake in rodents and humans, but the underlying mechanisms are unknown. Unlike most other fatty acids, MCFAs are absorbed from the intestine into the portal vei...