MSC-Derived Exosomes Protect Vertebral Endplate Chondrocytes against Apoptosis and Calcification via the miR-31-5p/ATF6 Axis

• मुख्य लेखकों: Lin Xie (लेखक), Zhenhao Chen (लेखक), Ming Liu (लेखक), Weibo Huang (लेखक), Fei Zou (लेखक), Xiaosheng Ma (लेखक), Jie Tao (लेखक), Jingkang Guo (लेखक), Xinlei Xia (लेखक), Feizhou Lyu (लेखक), Hongli Wang (लेखक), Chaojun Zheng (लेखक), Jianyuan Jiang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Apoptosis and calcification of endplate chondrocytes (EPCs) can exacerbate intervertebral disc degeneration (IVDD). Mesenchymal stem cell-derived exosomes (MSC-exosomes) are reported to have the therapeutic potential in IVDD. However, the effects and related mechanisms of MSC-exosomes on EPCs are st...