In-silico designing of a potent analogue against HIV-1 Nef protein and protease by predicting its interaction network with host cell proteins

• Hoofdauteurs: Shikha Pal (Auteur), Madhur Mishra (Auteur), D Raja Sudhakar (Auteur), Mohammed Haris Siddiqui (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: HIV-1 has numerous proteins encoded within its genome, which acquaints it with the required arsenal to establish a favorable host cell environment suitable for viral replication and pathogenesis. Among these proteins, one protein that is indispensable and ambiguous is the Nef protein. Ai...