Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

• Autores principales: Paul Capewell (Autor), Nicola J Veitch (Autor), C Michael R Turner (Autor), Jayne Raper (Autor), Matthew Berriman (Autor), Stephen L Hajduk (Autor), Annette MacLeod (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The three sub-species of Trypanosoma brucei are important pathogens of sub-Saharan Africa. T. b. brucei is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. T. b. rhodesiense and T. b. gambiense are able to resist lysis by TLF. There are two...