Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

• Egile Nagusiak: Paul Capewell (Egilea), Nicola J Veitch (Egilea), C Michael R Turner (Egilea), Jayne Raper (Egilea), Matthew Berriman (Egilea), Stephen L Hajduk (Egilea), Annette MacLeod (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The three sub-species of Trypanosoma brucei are important pathogens of sub-Saharan Africa. T. b. brucei is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. T. b. rhodesiense and T. b. gambiense are able to resist lysis by TLF. There are two...