Selection of an Aptamer against the Enzyme 1-deoxy-D-xylulose-5-phosphate Reductoisomerase from <i>Plasmodium falciparum</i>

• Main Authors: Carlota Roca (Author), Yunuen Avalos-Padilla (Author), Beatriz Prieto-Simón (Author), Valentín Iglesias (Author), Miriam Ramírez (Author), Santiago Imperial (Author), Xavier Fernàndez-Busquets (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The methyl erythritol phosphate (MEP) pathway of isoprenoid biosynthesis is essential for malaria parasites and also for several human pathogenic bacteria, thus representing an interesting target for future antimalarials and antibiotics and for diagnostic strategies. We have developed a DNA aptamer...