Isavuconazole Exposure in Critically Ill Patients Treated with Extracorporeal Membrane Oxygenation: Two Case Reports and a Narrative Literature Review

• Main Authors: Beatrijs Mertens (Author), Omar Elkayal (Author), Erwin Dreesen (Author), Joost Wauters (Author), Philippe Meersseman (Author), Yves Debaveye (Author), Karlien Degezelle (Author), Pieter Vermeersch (Author), Matthias Gijsen (Author), Isabel Spriet (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Effective dosing of isavuconazole in patients supported by extracorporeal membrane oxygenation (ECMO) is important due to the role of isavuconazole as a first-line treatment in patients with influenza- and COVID-19-associated pulmonary aspergillosis. To date, robust pharmacokinetic data in patients...