Research progress on substitution of in vivo method(s) by in vitro method(s) for human vaccine potency assays

• Main Authors: Xuanxuan Zhang (Author), Xing Wu (Author), Qian He (Author), Junzhi Wang (Author), Qunying Mao (Author), Zhenglun Liang (Author), Miao Xu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction Potency is a critical quality attribute for controlling quality consistency and relevant biological properties of vaccines. Owing to the high demand for animals, lengthy operations and high variability of in vivo methods, in vitro alternatives for human vaccine potency assays are extens...