Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• প্রধান লেখক: Grazyna Adler (লেখক), Izabela Uzar (লেখক), Amina Valjevac (লেখক), Emina Kiseljakovic (লেখক), Emir Mahmutbegovic (লেখক), Nermin N. Salkic (লেখক), Mateusz A. Adler (লেখক), Nevena Mahmutbegovic (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...