Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Egile Nagusiak: Grazyna Adler (Egilea), Izabela Uzar (Egilea), Amina Valjevac (Egilea), Emina Kiseljakovic (Egilea), Emir Mahmutbegovic (Egilea), Nermin N. Salkic (Egilea), Mateusz A. Adler (Egilea), Nevena Mahmutbegovic (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...