Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Auteurs principaux: Grazyna Adler (Auteur), Izabela Uzar (Auteur), Amina Valjevac (Auteur), Emina Kiseljakovic (Auteur), Emir Mahmutbegovic (Auteur), Nermin N. Salkic (Auteur), Mateusz A. Adler (Auteur), Nevena Mahmutbegovic (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...