Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Үндсэн зохиолчид: Grazyna Adler (Зохиогч), Izabela Uzar (Зохиогч), Amina Valjevac (Зохиогч), Emina Kiseljakovic (Зохиогч), Emir Mahmutbegovic (Зохиогч), Nermin N. Salkic (Зохиогч), Mateusz A. Adler (Зохиогч), Nevena Mahmutbegovic (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...