Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Váldodahkkit: Grazyna Adler (Dahkki), Izabela Uzar (Dahkki), Amina Valjevac (Dahkki), Emina Kiseljakovic (Dahkki), Emir Mahmutbegovic (Dahkki), Nermin N. Salkic (Dahkki), Mateusz A. Adler (Dahkki), Nevena Mahmutbegovic (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...