Transgenic Overexpression of Galectin-3 in Pancreatic β Cells Attenuates Hyperglycemia in Mice: Synergistic Antidiabetic Effect With Exogenous IL-33

• Main Authors: Nemanja Jovicic (Author), Ivica Petrovic (Author), Nada Pejnovic (Author), Biljana Ljujic (Author), Marina Miletic Kovacevic (Author), Sladjana Pavlovic (Author), Ilija Jeftic (Author), Aleksandar Djukic (Author), Ivan Srejovic (Author), Vladimir Jakovljevic (Author), Miodrag L Lukic (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Galectin-3 (Gal-3) has diverse roles in inflammatory and autoimmune diseases. There is evidence that Gal-3 plays a role in both type 1 and type 2 diabetes. While the role of Gal-3 expression in immune cells invading the pancreatic islets in the experimental model of type 1 diabetes mellitus has been...