Desipramine Activated Bcl-2 Expression and Inhibited Lipopolysaccharide-Induced Apoptosis in Hippocampus-Derived Adult Neural Stem Cells

• Main Authors: Yu-Yin Huang (Author), Chi-Hsien Peng (Author), Yi-Ping Yang (Author), Chih-Chiau Wu (Author), Wen-Ming Hsu (Author), Hsiao-Jung Wang (Author), Kwok-Han Chan (Author), Yi-Pen Chou (Author), Shih-Jen Chen (Author), Yuh-Lih Chang (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Desipramine (DP) is a tricyclic antidepressant used for treating depression and numerous other psychiatric disorders. Recent studies have shown that DP can promote neurogenesis and improve the survival rate of hippocampal neurons. However, whether DP induces neuroprotection or promotes the different...