Simultaneous analysis of allopurinol and oxypurinol using a validated liquid chromatography-tandem mass spectrometry method in human plasma

• Váldodahkkit: Dhiraj M. Rathod (Dahkki), Keyur R. Patel (Dahkki), Hiren N. Mistri (Dahkki), Arvind G. Jangid (Dahkki), Pranav S. Shrivastav (Dahkki), Mallika Sanyal (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2017-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The present study describes a simple, reliable and reproducible liquid chromatography-tandem mass spectrometry method (LC-MS/MS) for the simultaneous determination of allopurinol and its active metabolite, oxypurinol in human plasma for a pharmacokinetic/bioequivalence study. After protein precipita...