Engraftment of human mesenchymal stem cells in a severely immunodeficient mouse

• Main Authors: Yuko Kato (Author), Yusuke Ohno (Author), Ryoji Ito (Author), Takeshi Taketani (Author), Yumi Matsuzaki (Author), Satoru Miyagi (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The transplantation of human mesenchymal stromal/stem cells (hMSCs) has potential as a curative and permanent therapy for congenital skeletal diseases. However, the self-renewal and differentiation capacities of hMSCs markedly vary. Therefore, cell proliferation and trilineage differentiati...