In Vivo and In Vitro Treatment With Edaravone Promotes Proliferation of Neural Progenitor Cells Generated Following Neuronal Loss in the Mouse Dentate Gyrus

• Main Authors: Maho Kikuta (Author), Tatsuo Shiba (Author), Masanori Yoneyama (Author), Koichi Kawada (Author), Taro Yamaguchi (Author), Eiichi Hinoi (Author), Yukio Yoneda (Author), Kiyokazu Ogita (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Edaravone is clinically used in Japan for treatment of patients with acute cerebral infarction. To clarify the effect of edaravone on neurogenesis in the hippocampus following neuronal injury in the hippocampal dentate gyrus, we investigated the effect of in vitro and in vivo treatment with edaravon...