Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK-AMPK-Sirt1-Associated Signaling Pathway in Mouse Models

• Main Authors: Liang-Hsuan Chien (Author), Chien-Ta Wu (Author), Jeng-Shyan Deng (Author), Wen-Ping Jiang (Author), Wen-Chin Huang (Author), Guan-Jhong Huang (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute kidney injury (AKI) is a sudden reduction in kidney activity and has a high mortality rate. Salvianolic acid C (SAC), one of the main polyphenolic components of <i>Salvia miltiorrhiza</i>, displays significant pharmacologically active effects. An animal model of cisplatin-induced k...