Novel CDKs inhibitors for the treatment of solid tumour by simultaneously regulating the cell cycle and transcription control
A novel series of cyclin-dependent kinases (CDKs) inhibitors, which play critical roles in the cell cycle control and regulation of cell transcription, were synthesised. A systematic study of enzymatic and cellular assays led to the identification of compound X22 with a nanomolar potency against CDK...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2020-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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