The Synthetic Curcumin Analog HO-3867 Rescues Suppression of PLAC1 Expression in Ovarian Cancer Cells

• Główni autorzy: Eric J. Devor (Autor), Brandon M. Schickling (Autor), Jace R. Lapierre (Autor), David P. Bender (Autor), Jesus Gonzalez-Bosquet (Autor), Kimberly K. Leslie (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Elevated expression of placenta-specific protein 1 (PLAC1) is associated with the increased proliferation and invasiveness of a variety of human cancers, including ovarian cancer. Recent studies have shown that the tumor suppressor p53 directly suppresses PLAC1 transcription. However, mutations in p...