Exploring the in vitro and in vivo anticancer activity of lasiokaurin on nasopharyngeal carcinoma

• Main Authors: Huanhuan Pu (Author), Jinrong Lin (Author), Li-Sha Shen (Author), Yu-Shan Lin (Author), Rui-Hong Gong (Author), Guo Qing Chen (Author), Sibao Chen (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To evaluate the anticancer activity of the natural diterpenoid lasiokaurin (LAS) against nasopharyngeal carcinoma (NPC) both in vitro and in vivo, along with investigating its underlying mechanism. Methods: MTT and colony formation assays were used to assess cell viability. Flow cytometry...