Changes in cerebral oxidative metabolism during neonatal seizures following hypoxic ischemic brain injury

• Main Authors: Subhabrata Mitra (Author), Gemma Bale (Author), Sean Mathieson (Author), Cristina Uria-Avellanal (Author), Judith Meek (Author), Ilias Tachtsidis (Author), Nicola Robertson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Seizures are common following hypoxic ischemic brain injury in newborn infants. Prolonged or recurrent seizures have been shown to exacerbate neuronal damage in the developing brain, however the precise mechanism is not fully understood. Cytochrome-c-oxidase is responsible for more than 90% of ATP p...