Extracellular lipids of Candida albicans biofilm induce lipid droplet formation and decreased response to a topoisomerase I inhibitor in dysplastic and neoplastic oral cells

• Main Authors: Freddy Humberto MARIN-DETT (Author), Jonatas Erick Maimoni CAMPANELLA (Author), Eliane TROVATTI (Author), Maria Célia BERTOLINI (Author), Carlos Eduardo VERGANI (Author), Paula Aboud BARBUGLI (Author)
• Format: Book
• Published: University of São Paulo, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective Some microorganisms, i.e., Candida albicans, have been associated with cancer onset and development, although whether the fungus promotes cancer or whether cancer facilitates the growth of C. albicans is unclear. In this context, microbial-derived molecules can modulate the growth...