Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene

• Main Authors: Jerome Clifford Foo (Author), Valentina Vengeliene (Author), Hamid Reza Noori (Author), Ikuhiro Yamaguchi (Author), Kenji Morita (Author), Toru Nakamura (Author), Yoshiharu Yamamoto (Author), Rainer Spanagel (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pharmacotherapeutic options supporting the treatment of alcohol dependence are recommended and available but underutilized, partly due to questions about efficacy. Nalmefene, a μ-opioid receptor antagonist and partial kappa receptor agonist, is recommended for reduction of alcohol consum...