Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)

• Main Authors: Liliana Ferreira (Author), Edite Teixeira- (Author), Filipa Pinto (Author), Belmiro Parada (Author), Cristina Mega (Author), Helena Vala (Author), Rui Pinto (Author), Patrícia Garrido (Author), José Sereno (Author), Rosa Fernandes (Author), Paulo Santos (Author), Isabel Velada (Author), Andreia Melo (Author), Sara Nunes (Author), Frederico Teixeira (Author), Flávio Reis (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this paper is to evaluate the chronic effect of sitagliptin on metabolic profile, inflammation, and redox status in the Zucker Diabetic Fatty (ZDF) rat, an animal model of obese type 2 diabetes. Diabetic and obese ZDF (fa/fa) rats and their controls (ZDF +/+) were treated during 6 wee...