The dynamic equilibrium between the protective and toxic effects of matrine in the development of liver injury: a systematic review and meta-analysis

• Main Authors: Weiyi Feng (Author), Te-chan Kao (Author), Jiajie Jiang (Author), Xinyu Zeng (Author), Shuang Chen (Author), Jinhao Zeng (Author), Yu Chen (Author), Xiao Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Matrine, an alkaloid derived from the dried roots of Sophora flavescens Aiton, has been utilized for the treatment of liver diseases, but its potential hepatotoxicity raises concerns. However, the precise condition and mechanism of action of matrine on the liver remain inconclusive. Ther...