Nonsense Suppression Therapy: An Emerging Treatment for Hereditary Skin Diseases

• Główni autorzy: Jiangfan Yu (Autor), Bingsi Tang (Autor), Xinglan He (Autor), Puyu Zou (Autor), Zhuotong Zeng (Autor), Rong Xiao (Autor)
• Format: Książka
• Wydane: Medical Journals Sweden, 2022-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Nonsense mutations cause the premature termination of protein translation via premature termination codons (PTCs), leading to the synthesis of incomplete functional proteins and causing large numbers of genetic disorders. The emergence of nonsense suppression therapy is considered to be an effective...