Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators

The synthesis and carbonic anhydrase (CA; EC 4.2.1.1) activating effects of a series of oxime ether-based amino alcohols towards four human (h) CA isoforms expressed in human brain, hCA I, II, IV and VII, are described. Most investigated amino alcohol derivatives induced a consistent activation of t...

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Main Authors: Alessio Nocentini (Author), Doretta Cuffaro (Author), Lidia Ciccone (Author), Elisabetta Orlandini (Author), Susanna Nencetti (Author), Elisa Nuti (Author), Armando Rossello (Author), Claudiu T. Supuran (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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