Pleiotropic Long-Term Effects of Atorvastatin on Posttraumatic Joint Contracture in a Rat Model

• Main Authors: Erik Wegner (Author), Ekaterina Slotina (Author), Tim Mickan (Author), Sebastian Truffel (Author), Charlotte Arand (Author), Daniel Wagner (Author), Ulrike Ritz (Author), Pol M. Rommens (Author), Erol Gercek (Author), Philipp Drees (Author), Andreas Baranowski (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The antifibrotic effect of atorvastatin has already been demonstrated in several organ systems. In the present study, a rat model was used to investigate the effect of atorvastatin on posttraumatic joint contracture. Forty-eight Sprague Dawley rats were equally randomized into an atorvastatin group...