In Vivo Dopamine Neuron Imaging-Based Small Molecule Screen Identifies Novel Neuroprotective Compounds and Targets

• Main Authors: Gha-hyun J. Kim (Author), Han Mo (Author), Harrison Liu (Author), Meri Okorie (Author), Steven Chen (Author), Jiashun Zheng (Author), Hao Li (Author), Michelle Arkin (Author), Bo Huang (Author), Su Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is the second most common neurodegenerative disorder with prominent dopamine (DA) neuron degeneration. PD affects millions of people worldwide, but currently available therapies are limited to temporary relief of symptoms. As an effort to discover disease-modifying ther...