Fangchinoline induces antiviral response by suppressing STING degradation

• Main Authors: Jinyong Wang (Author), Fang Xie (Author), Xin Jia (Author), Xuejiao Wang (Author), Lingdong Kong (Author), Yiying Li (Author), Xue Liang (Author), Meiqi Zhang (Author), Yuting He (Author), Wandi Feng (Author), Tong Luo (Author), Yao Wang (Author), Anlong Xu (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The stimulator of interferon genes (STING), an integral adaptor protein in the DNA-sensing pathway, plays a pivotal role in the innate immune response against infections. Additionally, it presents a valuable therapeutic target for infectious diseases and cancer. We observed that fangchinoline (Fan),...