GEMMs as preclinical models for testing pancreatic cancer therapies

• Auteurs principaux: Aarthi Gopinathan (Auteur), Jennifer P. Morton (Auteur), Duncan I. Jodrell (Auteur), Owen J. Sansom (Auteur)
• Format: Livre
• Publié: The Company of Biologists, 2015-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Pancreatic ductal adenocarcinoma is the most common form of pancreatic tumour, with a very limited survival rate and currently no available disease-modifying treatments. Despite recent advances in the production of genetically engineered mouse models (GEMMs), the development of new therapies for pan...